专利名称:2-substituted alkylaminopyrimidones useful
as H.sub.2 - antagonists and antiinflamatoryagents
发明人:Charon R. Ganellin,Robert J. Ife,David A. A.
Owen
申请号:US06/729448申请日:19850501公开号:US04639519A公开日:19870127
摘要:The compounds are isoureas and isothioureas which have an O- or S-alkylpyrimidone substituent and which are histamine H.sub.2 - antagonists andantiinflammatory agents.
A specific compound of this invention is 2- 5-(O-isoureido)pentylamino!-5-(6-methyl- 3-pyridylmethyl)- 4-pyrimidone.
申请人:SMITH KLINE & FRENCH LABORATORIES LIMITED
代理人:Linda E. Hall,Stuart R. Suter,Alan D. Lourie
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